Mannitol

Mpressol
Mpressol | Mannitol | Diluent / Filler
CAS No. 69-65-8
CAS No. 69-65-8
Mannitol, a naturally occurring polyol, is a cornerstone in pharmaceutical formulations. It serves as an inert filler, diluent, and sweetening agent across a wide range of dosage forms, from tablets to powders.


Key Features:
  • Non-Hygroscopic Stability : Zero moisture uptake at high humidity (-80% RH), protecting moisture-sensitive APls from degradation.
  • Chemical Inertness: Highly stable and inert with APls, preventing Maillard reactions or other incompatibilities.
  • Water Solubility & Wetting : Freely soluble (-18-20% w/v at 20°C), aiding rapid disintegration and drug release.
  • Organoleptic Benefits : Mild sweet taste and cooling sensation improve mouthfeel for chewable and orally disintegrating forms
  • Excellent Compressibility : Modern grades yield robust tablets under direct compression and exhibit low friability.

Applications:
  • Tablets (especially ODTs & chewables)
  • Capsules
  • Sachets / dry syrups
  • Nutraceuticals (protein powders, supplements)

Advantages :

  • Excellent Flow & Compressibility : Engineered grades of Mannitol enable efficient direct compression, yielding robust and hard tablets.
  • Stability & Low Moisture Uptake : Its non-hygroscopic nature protects moisture-sensitive drugs, enhancing shelf-life stability.
  • Inert Carrier : Mannitol is compatible with a wide range of APIs, ensuring no adverse chemical interactions.
  • Taste-Masking & Patient Experience : Its mild sweetness and cooling effect improve palatability and patient compliance, especially for pediatrics.
Mpressol is a pharmaceutical-grade excipient based on mannitol and it is commonly used as a filler and binder in oral solid and liquid dosage forms. Mannitol excipient is known for its consistent quality and reliable performance in pharmaceutical manufacturing.
Mpressol (Mannitol excipient) functions primarily as a filler and binder, offering excellent flowability, compressibility, and chemical stability in pharmaceutical oral dosage forms.

Mannitol shows good compatibility with a wide range of active pharmaceutical ingredients (APIs) and is commonly used in pharmaceutical formulations where stability and patient acceptability are critical.

Due to its non-hygroscopic nature, chemical inertness, and good mouthfeel properties, Mannitol excipient supports stable pharmaceutical formulations, consistent processing, and enhanced patient compliance.
Mpressol is a versatile pharma excipient for both oral solid dosage forms (OSDs) and oral liquid formulations such as tablets, capsules, syrups, and suspensions.

Due to its pleasant mouthfeel properties, Mpressol (mannitol excipient) is also used in chewable tablets and Orodispersible / Orally Disintegrating Tablets (ODTs).

Yes, all pharmaceutical excipients from Gangwal Healthcare, including mannitol, are manufactured under stringent quality systems, ensuring compliance with applicable pharmacopoeial and regulatory requirements.

Gangwal Healthcare is a trusted pharmaceutical excipient manufacturer, known for consistent quality, GMP-aligned manufacturing practices, and a strong focus on customer and formulation needs.

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